When Mr. Putter catches a cold, his friend Mrs. Teaberry sends over some special treats to help him feel better.

Madeline, smallest and naughtiest of the twelve little charges of Miss Clavel, wakes up one night with an attack of appendicitis.

When the reindeer get bad colds, Santa Claus wonders who will be able to pull his sleigh on Christmas Eve.

All his life Benji, now ten, has been sickly and he has long been targeted by the school bully, but after a seizure Benji gets a therapy dog that is not only big enough to protect him, it can also talk.

On a rainy day when Baby Duck is sick with a cold, her grandfather cheers her up by showing her family photographs.

Cynthia the centipede, Harold the hamster, Tiffany the turtle, and other animals suffer from various injuries or illnesses.

When Sam has a cough, Mrs. Bear tends to him all through the cold night.

Johnny Lion has a bad cold and the medicine he takes and the dreams he has are both terrible.

Junie B.'s journal entries start with Room One's stomach virus excitement, the first-grade Columbus Day play, and getting the part of the Pinta, the fastest ship.